Detailed Program

7:00 a.m. - 6:00 p.m.

Registration

Concourse C

8:30 a.m. - 5:00 p.m.

Satellites
*Registration Fee Applies

Fetal Physiology

E219BC

Placenta Satellite

E219D

Endometrial Satellite

E219A

Ovarian Biology Satellite

E221

Preterm Birth International Collaborative (PREBIC) Satellite

E218

Myometrium and Parturition Satellite

E217

5:15 p.m. - 6:15 p.m.

Early Career Forum
*Ticketed

E217

6:30 p.m. - 8:00 p.m.

Welcome Reception

Richardson Ballroom CD

7:00 a.m. - 6:00 p.m.

Registration

Concourse C

7:00 a.m. - 8:00 a.m.

Light Continental Breakfast

Pre-Function 1
(outside of Richardson Ballroom CD)

8:00 a.m. - 8:10 a.m.

Presidential Welcome
Ayman Al-Hendy, MD, PhD

Richardson Ballroom CD

8:10 a.m. - 9:00 a.m.

President's Distinguished Lecture I

Valerie Montgomery Rice, MD, FACOG
President and CEO, Morehouse School of Medicine

Cultivating Inclusive Excellence: How diversity fuels innovation in biomedical research

Richardson Ballroom CD

9:00 a.m. - 10:00 a.m.

President's New Investigator Plenary
Supported by the Past Presidents' Fund
Moderators:
Sandy Davidge, PhD, FCAHS, FRSC, FRCOG

Richardson Ballroom CD

9:00 a.m. - 9:15 a.m.

O-001: Translatable Programming of Cardiovascular Reactivity in Adult Offspring in an Ovine Model of Maternal Obesity during Pregnancy
Skaai Davison, Rachael C Crew, Youguo Niu, Sage G Ford, Clement L Cahen, Anna LK Cochrane, Michael P Murphy, Susan E Ozanne, Dino A Giussani
 

9:15 a.m. - 9:30 a.m.

O-002: High-Dimensional Imaging Reveals Eutopic Endometrial Cell Frequency and Functional Shifts in Endometriosis
Maïgane G Diop, Dorien Feyaerts, Jakob Einhaus, Juan Irwin, Adam Bonham, Ina Stelzer, David Stevenson, Marina Sirota, Catherine Blish, Linda Giudice, Brice Gaudillière

9:30 a.m. - 9:45 a.m.

O-003: Revolutionizing Endometrial Repair: Hybrid Endometrial-Derived Hydrogel and Human Endometrial Organoids Synergize for Uterine Regeneration in an Immunocompetent Murine Model
Clara Bueno-Fernandez, María Gómez-Álvarez, Marcos Agustina-Hernández, Emilio Francés-Herrero, Ana Díaz, Amparo Faus, Paula Alonso-Frías, Nadaya Corpas, Antonio Pellicer, Irene Cervelló

9:45 a.m. - 10:00 a.m.

O-004: Uncovering Immune Responses at the Maternal-Fetal Interface Triggered by IL-9, a T-cell Cytokine, during Preterm Labor
Dustyn B. Levenson, Valeria Garcia-Flores, Roger Pique-Regi, Yi Xu, Nardhy Gomez-Lopez

10:00 a.m. - 12:00 p.m.

Poster Session I

Hall C2

12:00 p.m. - 1:00 p.m.

Lunch & Learn Symposium: Translating Discovery to Improved Reproductive Health
*Boxed lunches available for purchase through online registration only.

Richardson Ballroom CD

Moderators:
Jessica Garcia de Paredes, MD
Kristin Connor, PhD

Speakers:

O. Sandra Madueke-Laveaux, MD, MPH
Associate Professor, Obstetrics & Gynecology
Division of Minimally Invasive Gynecologic Surgery
Director, Center for Advanced Treatment and Research (CATeR) of Uterine Fibroids.
Gynecologic Surgery Liaison, Bloodless Medicine Program
University of Chicago

Irene Aninye, PhD
Chief Science Officer
Society for Women's Health Research

Speaker III Details Coming Soon

1:15 p.m. - 3:15 p.m.

Concurrent Mini-Symposia I

Effects of placental inflammation on fetal development

Moderators:
Elizabeth Enninga, PhD
Amélie Collins, MD, PhD

E217

1:15 p.m. - 1:45 p.m.

The mysteries of Fetal inflammatory response syndrome
Suhas Kallapur, MD

1:45 p.m. - 2:15 p.m.

Using monkey models to define the fetal immune response to prenatal inflammation
Claire Chougnet, PhD

2:15 p.m. - 2:45 p.m.

How does maternal immune activation affect the placenta?
Stephen Renaud, PhD

2:45 p.m. - 3:15 p.m.

Beyond folate: immune and  nutrient clues to placental maldevelopment in fetal spina bifida.
Kristin Connor, PhD

The Intersection of Biology and Bias in Substance Use Disorders

Moderators:
Jamie Lo, MD
Panicos Shangaris, MSc(Dist) MRCOG PhD

E219A

1:15 p.m. - 1:45 p.m.

Opioid Use in Pregnancy: Defining the Placenta’s Role in Opioid Transport, Metabolism and Neonatal Withdrawal
Courtney D. Townsel, MD, MSc

1:45 p.m. - 2:15 p.m.

Structural Bias at the intersection of substance use and other marginalized identities: A recipe for preventable maternal morbidity and mortality
Michelle Debbink, MD, PhD

2:15 p.m. - 2:45 p.m.

Perinatal cannabinoid exposure in rat model leads to fetal growth restriction and placental vascular defects
David Natale, PhD

2:45 p.m. - 3:15 p.m.

Test and consequence: Care and Ethics during the birthing hospitalization
Mishka Terplan, MD, MPH

Impact of environmental pollutants on female reproductive health. From reproduction and beyond

Moderators:
Francisco Dominguez, PhD
Shruthi Mahalingaiah, MD, MS

E219BC

1:15 p.m. - 1:45 p.m.

Prenatal PFAS exposure and developmental neurotoxicity
Liping Feng, MD

1:45 p.m. - 2:15 p.m.

The role of environmental pollutants as modifiers of menopausal timing. Links with ovarian reserve
John F. Randolph, MD

2:15 p.m. - 2:45 p.m.

Endocrine disruptors and cardiometabolic health from pregnancy to perimenopause
Tamarra James-Todd, MPH, PhD

2:45 p.m. - 3:15 p.m.

Endocrine-disrupting chemicals and incidence of uterine leiomyomata: findings from the SELF cohort
Lauren Wise, ScD

Senescence and Gynecologic Disorders: Role in Pathophysiology and Treatment Opportunities

Moderators:
Mostafa A. Borahay, MD, PhD
María Florián-Rodríguez, MD

E219D

1:15 p.m. - 1:45 p.m.

Title Coming Soon
Amanda Kallen, MD

1:45 p.m. - 2:15 p.m.

Ovarian aging and strategies to reactivate ovarian function
Sonia Herraiz, PhD

2:15 p.m. - 2:45 p.m.

Cellular senescence and ovarian aging: mapping senescent cells in the postmenopausal human ovary
Francesca Duncan, PhD

2:45 p.m. - 3:15 p.m.

Senescence and immune system in fibroids
Jennifer Elisseeff, PhD

3:15 p.m. - 3:30 p.m.

Coffee Break

Pre-Function 2
(outside of Richardson Ballroom AB)

3:30 p.m. - 5:30 p.m.

Concurrent Oral Presentations I

Clinical and Translational Perinatology I

Moderators:
Catherine Spong, MD
Jennifer Woo, PhD, CNM/WHNP

E217

3:30 p.m. - 3:45 p.m.

O-005: Plasma Cell Free (PCF) NAMPT Expression at 12-20 Weeks in Women Destined for Early Onset Preeclampsia (EOP) with Delivery <34 Weeks
Carl P Weiner, Howard S Cuckle, Susan E Carlson, Ira Bernstein

3:45 p.m. - 4:00 p.m.

O-006: Maternal Plasma miRNAs Predict Subsequent Adverse Pregnancy Outcome as Early as 12 Weeks’ Gestation
Sung Hye Kim, Lucia Riaposova, Maria Arianoglou, David A MacIntyre, Lynne Sykes, Phillip R Bennett, Vasso Terzidou

4:00 p.m. - 4:15 p.m.

O-007: Amniotic Fluid Extracellular Vesicles Provide Proteomic Insights into the Pathophysiology of Congenital Cytomegalovirus Infection
Ishara Atukorala, Luc De Catte, Sally Beard, Ching-Seng Ang, Susan Walker, Natalie Hannan, Lisa Hui

4:15 p.m. - 4:30 p.m.

President's Presenter Award
O-008: Reducing Health Inequities in Maternity Care: Impact of Integrated Maternity Care on Adverse Pregnancy Outcomes Among Women in a Socioeconomically Vulnerable Situation
Anne Hermans, Loes Bertens, Jasper Been, Arie Franx, Jacoba Van Der Kooy

4:30 p.m. - 4:45 p.m.

President's Presenter Award
O-009: Increased Risk of Perinatal Mental Disorders Among the Transgender Population: A Real-World Investigation Using US Electronic Health Records
Tina Yi Jin Hsieh, Maria Bazan, Anna Modest, James Cheng-Chung Wei, Chi-Fong Wang

4:45 p.m. - 5:00 p.m.

O-010: Racial and Ethnic Disparities in Maternal Anemia and Risk of Postpartum Hemorrhage Requiring Blood Transfusion
Jamie A. Green, Tiffany Mateo, Frank I. Jackson, Insaf Kouba, Luis A. Bracero, Kristen Demertzis, Matthew J. Blitz

5:00 p.m. - 5:15 p.m.

O-011: The Influence of Childhood Abuse, Neglect, and Household Dysfunction on Postpartum Opioid Use
Nidhee Reddy, Elizabeth Sherwin, Janet Hurtado, Sam Simpson, Jordan Burgess, Noor Joudi, Metabel Markwei, Miriam Schultz, Pervez Sultan, Brendan Carvalho, Danielle Panelli

5:15 p.m. - 5:30 p.m.

O-112: Gestational Diabetes Mellitus: Predictors of Pharmacotherapy Initiation
Candace Levian, Mariam Naqvi, Alexandra Navarrete, Mona Garcia, Tania F Esakoff

Gynecology I

Moderators:
Warren Nothnick, PhD
Aymara Mas Perucho, PhD

3:30 p.m. - 3:45 p.m.

O-013: Single-Nucleus Sequencing of Archival DIE Lesions Uncovers Local Dienogest Effects and Identifies Novel Treatment Strategies for Refractory Patients
Brett D. McKinnon, Lea Duempelmann, Jitka Skrabalova, Michael D Mueller, Konstantinos Nirgianakis

3:45 p.m. - 4:00 p.m.

O-014: Development of an In Vitro Model of the Cervicovaginal Interface for Mechanistic Investigation of Infection
Filipa Ribeiro, Katherine M. Nelson, Jason P. Gleghorn

4:00 p.m. - 4:15 p.m.

O-015: TF-CAR-NK Cells as an Immunotherapy for Endometriosis.
Ramanaiah Mamillapalli, Graciela Krikun, Gawde Nimisha, Zhiwei Hu, Hugh S Taylor

4:15 p.m. - 4:30 p.m.

Early Career Investigator Award
O-016: FOXA2 Loss Results an Increase of Endometriosis Incidence as Well as Epithelial PGR Loss, and LIF Reveals a Therapeutic Effect for Endometriosis
Md Saidur Rahman, Tae Hoon Kim, Breton F. Barrier, Thomas E. Spencer, Andrew M. Kelleher, Jae-Wook Jeong

4:35 p.m. - 4:45 p.m.

President's Presenter Award
O-017: Development of a Microphysiological Model to Study Endometriosis Lesions
Lauren Pruett, Laura Bahlmann, Ryan Ogi, Linda Griffith

4:45 p.m. - 5:00 p.m.

O-018: Spatial Transcriptomics Identifies Immune Cell Dysregulation in Adenomyosis, Endometriosis, and Fibroids
Alison Maclean, Emily Johnson, Eva Caamano-Gutierrez, Dharani K Hapangama

5:00 p.m. - 5:15 p.m.

O-019: A Novel Pre-Clinical Model of Excessive Endometrial Inflammation Causing Heavy Menstrual Bleeding
Bethan Rowley, Rocío Martínez Aguilar, Rebecca Gentek, Kristina Gemzell Danielsson, Adrian Freeman, Jacqueline Maybin

5:15 p.m. - 5:30 p.m.

O-020: Inhibiting Fatty Acid Synthesis As a Potential Targeted Therapy to Treat Endometriosis In Patients With an ARID1A Mutation
Daniëlle Peterse, Samuel Garrard, Dayana Alay Gonzalez, Caroline Stone, Michael Rogers.

Parturition I

Moderators:
Matt Kemp, PhD
Lynne Sykes, BSc, MBBS, PhD

E219A

3:30 p.m. - 3:45 p.m.

O-021: M1 Macrophages are a Source of IL-1α: A Driver of Progesterone Metabolism and Myometrial Contraction
Lubna Nadeem, Benjamin Matthews, Adam Boros-Rausch, Eduardo Aguiar, Oksana Shynlova, Stephen Lye

3:45 p.m. - 4:00 p.m.

O-022: Molecular Detection of Group B Streptococcus Carriage in Pregnant Women
Francesca Gaccioli, Eleonor Richards, Katie Stephens, D Stephen Charnock-Jones, Gordon CS Smith

4:00 p.m. - 4:15 p.m.

O-023: Administration of Proteins Secreted by the Placenta Markedly Improves Lung and Hepatic Molecular Outcomes in Premature Guinea Pigs
Avery C Kramer, Kelsey J Faer, Rebecca M Dyson, Alice Freeman, Theresa L Powell, Max Berry, Thomas Jansson

4:15 p.m. - 4:30 p.m.

O-024: 15dPGJ2 Prevents Maternal Stress Induced Preterm Birth in Mice
O. Guzeloglu-Kayisli, A. Ozmen, B. C. Un, B. Un, U. A Kayisli, I. Johnson, A. Thurman, M. Walters, D. Friend, C. J Lockwood

4:30 p.m. - 4:45 p.m.

Early Career Investigator Award
O-025: Concurrent Targeting of Connexin 43 and the β3 Adrenergic Receptor Relaxes Human Myometrium and Delays Birth in C57BL/6 Mice
Scott D Barnett, Iain L.O. Buxton

4:45 p.m. - 5:00 p.m.

O-026: A New Bedside Blood Test for Early Prediction of Adverse Prenatal Outcomes: From Bench to Clinical Implementation
Sylvain Ladame, Marc Soler, Brenna Parke, Vasso Terzidou, Phillip Bennett, Lynne Sykes, David MacIntyre

5:00 p.m. - 5:15 p.m.

O-027: Molecular Effects in Human Placenta Due to Heat Exposure during Pregnancy
Khondoker Mehedi Akram, Eleanor Dodd, Dilly Anumba

5:15 p.m. - 5:30 p.m.

O-028: Indigenous First Nations Maternal Mortality, Food Security, and Land Use.
Contessa Ricci, Melodi Wynne, Lynette Pflueger, Julie Postma, Luciana Hebert.

Placenta I

Moderators:
Owen Vaughan, PhD
Michal Silber, MD, PhD

E219BC

3:30 p.m. - 3:45 p.m.

O-029: Pregnancy Hormones Downregulate ILC3 Cytokine Production to Prevent Trophoblast Impairment
Chiara A. Drechsler, Jens Ehrhardt, Marek Zygmunt, Damián O. Muzzio

3:45 p.m. - 4:00 p.m.

O-030: Environmental Contaminants Identified via Non-Targeted Plasma Metabolomics in Euploid Early Pregnancy Loss
Dimitri Abrahamsson, Bahar D Yilmaz, Xiaowen Ji, Amrita Nagasuri, Mona Aminbeidokhti, David Huang, Hakan Cakmak, Marcelle I Cedars, Tomiko Oskotsky, Marina Sirota, Aleksandar Rajkovic

4:00 p.m. - 4:15 p.m.

O-031: Microparticles and Micropollutants in Human Umbilical Cord
Jacob Garcia, Rodrigo Weingrill, Johann Urschitz, Men-Jean Lee

4:15 p.m. - 4:30 p.m.

O-032: Identification and Validation of DNA Binding Factors That Control Differentiation of Human Trophoblast Stem Cells in 3D Culture
Danielle Sadowski, Cassandra Norbeck, Hannah Craven, Sunna Mujteba, Sarah Wernimont, Micah D Gearhart

4:30 p.m. - 4:45 p.m.

O-033: Nuclear Subtypes in the Giant, Multinucleated Placenta Syncytiotrophoblast Cell Respond to Environmental Cues
Madeline Keenen, Liheng Yang, Veronica Farmer, Carolyn Coyne, Amy Gladfelter

4:45 p.m. - 5:00 p.m.

Early Career Investigator Award
O-034: Natriuretic Peptide B Involvement in Hemochorial Placentation and Maternal Adaptations to Pregnancy
Marija Kuna, Esteban M. Dominguez, Khursheed Iqbal, Michael J. Soares

5:00 p.m. - 5:15 p.m.

President's Presenter Award
O-035: SARS-CoV-2 ORF3a-Mediated Modulation of Intercellular Dynamics via Tunneling Nanotubes and Extracellular Vesicles
Deepak Kumar, Indira U Mysorekar

5:15 p.m. - 5:30 p.m.

O-036: Placentas Exhibit Sexually Dimorphic Immune Responses to Circulating Cell-Free Mitochondrial DNA
Renee da Silva, Nataliia Hula, Desirae Escarela, Isabelle Gorham, Nicole Phillips, Styliani Goulopoulou

Maternal Biology and Health

Moderators:
Shathiyah Kulandavelu, PhD
Rafael Michita, PhD

E219D

3:30 p.m. - 3:45 p.m.

Early Career Investigator Award
O-037: A Single Nuclear and Spatial Transcriptomic Atlas of the Contractile and Atonic Gravid Human Uterus Reveals Two Distinct Smooth Muscle Cell Populations
Jessica Ansari, Daiana Fornes, Carsten Knutsen, Lynn Yang, Guillermina Michel, Alex Kum, Douglas Henze, Cristina Alvira, Stephen Quake, David Cornfield

3:45 p.m. - 4:00 p.m.

President's Presenter Award
O-038: Estradiol-17β Differentially Regulates the Expression and CBS/H₂S-Resposnive Sulfhydration of the Forming Subunits (α/β1/γ1) of Human Uterine Artery BK_Ca Channels in Pregnancy
Fategbe Tolulope Olamide

4:00 p.m. - 4:15 p.m.

O-039: Sex-Dependent Impaired Cardiac Mitochondrial Energetics in Late Gestation Ftal Sheep from Obese Pregnancy
Benjamin D Thackray, Anna LK Cochrane, Rachael C Crew, Youguo Niu, Skaai Davison, Lucrezia Zuccarelli, Michael P Murphy, Susan E Ozanne, Andrew J Murray, Dino A Giussani

4:15 p.m. - 4:30 p.m.

O-040: Pregnancy-Specific Programming of Hypertension and Vascular Dysfunction in Postpartum Rats Exposed to Gestational Intermittent Hypoxia
Ruolin Song, Pankaj Yadav, Alissa Hofmann, Jay Mishra, Sathish Kumar

4:30 p.m. - 4:45 p.m.

O-041: Placental Specific Knockdown of Adrenomedullin Improves GDM Symptoms in a Mouse Model of Diabetic Pregnancy
Kathleen A. Pennington, Simone Hernandez-Ruano, Moises Tacam, Manu Banadakoppa, Chandra Yallampalli

4:45 p.m. - 5:00 p.m.

Laxmi Baxi Award
O-042: Maternal Gut Histomorphometric Adaptations to High Fat Diet, Viral Infection, and Advancing Gestation: Implications for Pregnancy Health
Lucas Carvalho Cardoso, Thaina Ferraz, Sadra Mohammadkhani, Enrrico Bloise, Kristin Connor

5:00 p.m. - 5:15 p.m.

President's Presenter Award
O-043: Maternal Perceived Ethnic Discrimination Impacts Stress-Responsive Placental mRNA and miRNA
Francesca Carasi-Schwartz, Tomoko Kaneko-Tarui, Taysir Mahmoud, Sebastian Z. Ramos, Larry Feig, Perrie O'Tierney-Ginn

5:15 p.m. - 5:30 p.m.

O-044: Social Determinants of Health as Predictors of Increased Perinatal Morbidity and Mortality
Jameela Media, Nuong Truong, Abigail Winder, Haley Zanga, Genevieve Iben, Feffer Marina, Mary Murphy, Hannah Pope, Jessica Shaker, Mirelle Dawoud, Ann Lal

Reproductive Biology I

Moderators:
Elizabeth, Enninga, PhD
Yalda Afshar, MD,PhD

E221

3:30 p.m. - 3:45 p.m.

O-045: FOXL2 in the Development and Maintenance of Ovarian Cell Fate
Robin Lovell-Badge

3:45 p.m. - 4:00 p.m.

O-046: Increased Natural Killer Cell Activity in the Ovary During the Peri-Ovulatory Phase of the Ovarian Cycle
Lucy Salter, Natasha Thompson, Toby Lanser, Elizabeth Bonney, Dimitry Krementsov, Tia Y Brodeur

4:00 p.m. - 4:15 p.m.

O-047: Chromosomal Balance and Developmental Fate: A Tale of Monosomy 21 Facing Trisomy 21
Roberto Yagüe-Serrano, Andrea Palomar, Alicia Quiñonero, Sara Morales-Álvarez, Roberto González-Martín, Mireia Florensa, Francisco Domínguez, Imma Sánchez-Ribas, Amparo Mercader

4:15 p.m. - 4:30 p.m.

O-048: Novel Vasodilatory Role of Piezo1-BK_CaChannel Signaling in the Uterine Vasculature
German A Arenas, Ramon A Lorca

4:30 p.m. - 4:45 p.m.

O-049: The Microbiota Extends the Reproductive Lifespan by Safeguarding the Ovarian Reserve.
Sarah K Munyoki

4:45 p.m. - 5:00 p.m.

O-050: The Presence of an Endometrioma Adversely Impacts Cortical and Peri-Follicular Blood Flow in Ipsilateral Ovary, Potentially Contributing to Poor Oocyte Quality.
Pravin Goud, Olivia Camp, Anuradha Goud, Husam Abu-Soud

5:00 p.m. - 5:15 p.m.

O-051: Exploring the Adverse Effect and Mechanism of Microplastic Exposure on Human Endometrial Stromal Cell.
Suhra Kim, Hayan Kwon, Yun Ji Jung, Hyewon Hur, Yeji Lee, JoonHo Lee, Young-Han Kim, Hee Young Cho, Ho-Keun Kwon, Jinkee Hong, Yong-Sun Maeng, Ja-Young Kwon

5:15 p.m. - 5:30 p.m.

O-052: Progesterone Modulates the Immune Response to Support Preimplantation Embryonic Development in the Mouse Oviduct
Wipawee Winuthayanon

5:45 p.m. - 7:15 p.m.

Connection Corners
*Ticketed

Richardson Ballroom AB

7:00 a.m. - 6:00 p.m.

Registration

Concourse C

7:00 a.m. - 8:00 a.m.

Light Continental Breakfast

Pre-Function 1
(outside of Richardson Ballroom CD)

8:00 a.m. - 8:10 a.m.

Welcome & Announcements

Richardson Ballroom CD

8:10 a.m. - 9:00 a.m.

President's Distinguished Lecture II

Chuan He, PhD
John T. Wilson Distinguished Service Professor
University of Chicago, Department of Chemistry

Gene expression regulation by RNA methylation

Richardson Ballroom CD

9:00 a.m. - 11:00 a.m.

Poster Session II

Hall C2

11:00 a.m. - 12:30 p.m.

Concurrent Oral Presentations II

Developmental Programming I

Moderators:
Meghan Riddell, PhD
Enrico Barrozo, PhD

E217

11:00 a.m. - 11:15 a.m.

O-053: Circadian Controlled Gene Nocturnin is a Potential Link between Liver Steatosis in Fetuses and Offspring Exposed to the Intrauterine Environment of Preeclampsia
Swati Dahariya, Nevins Allyson, Tacam Moises, Jon Andrew Fuson, Simone Hernandez Ruano, Chandrasekhar Yallampalli, Manu Banadakoppa

11:15 a.m. - 11:30 a.m.

O-054: Large-Scale Maternal DNA Methylation Changes Identified Across Pregnancy
Timothy York

11:30 a.m. - 11:45 a.m.

O-055: Profiling T Cell Phenotypes Across G2 Pregnancies with Same versus New Paternity
Janelle Santos, Erik Jessen, Bohdana Fedyshyn, Iris Lin, Kevin Pavelko, Elizabeth Enninga

11:45 a.m. - 12:00 p.m.

O-056: Fetal Growth Restriction Dysregulates Circulating Immune Cells-Vascular Endothelial Cells Interaction and Endothelial Function
Dilen Kadlec, Xinran Yang, Isabelle Taft, Sean Limesand, Chi Zhou

12:00 p.m. - 12:15 p.m.

O-057: Elevated Maternal Testosterone Induces Neurodevelopmental and Behavioral Deficits in Rat Offspring
Sathish Kumar, Jay Mishra

12:15 p.m. - 12:30 p.m.

O-058: Advanced Maternal Age is Associated with Increased Offspring Birth Weight in a Nonhuman Primate Model
Mary Elaine Graham, Nathaniel O'Connell, Sarah Cilvik

Fetus I

Moderators:
Moderator I Details Coming Soon
Beth Allison, PhD

E218

11:00 a.m. - 11:15 a.m.

O-059: Double Deletion of the Two De Novo DNA Methyltransferases Alleviates Maternal Diabetes-Induced Congenital Heart Defects
Kunio Tanaka, Reece Albert, Yang Peixin

11:15 a.m. - 11:30 a.m.

O-060: Highland Ancestry Protects Against Hypoxia-Induced Embryonic Origins of Heart Disease
Sara Perelmuter, Carlos E Salinas, Carlos E Blanco, Lucas C Pantaleão, Youguo Niu, Susan E Ozanne, Dino A Giussani

11:30 a.m. - 11:45 a.m.

O-061: L1 Retrotransposon Activity Regulates Animal Behavior After Maternal Immune Activation.
Bailey Spiegelberg, Anindita Sarkar, Iryna Gallina, Ethan Tietze, Colleen Heller, Sarah Parylak, Meiyan Wang, Arianna Mei, Eunice Meija, Apua Paquola, Fred Gage, Jennifer Erwin

11:45 a.m. - 12:00 p.m.

Early Career Investigator Award
O-062: Human Pregnancy on a Chip: New Approach Methods to Advance Research in Reproductive Science
Ramkumar Menon, Ananth Kammala, Meredith Kelleher, Elizabeth Bonney, Moumita Chakraborty, Lauren Richardson

12:00 p.m. - 12:15 p.m.

President's Presenter Award
O-063: Branched-Chain Amino Acid Catabolism and TCA Cycle Progression is Lower in Growth Restricted Fetal Sheep Skeletal Muscle
Eileen I. Chang, Danika L. Ghiselli, Collin S. Painter, Michael L. Armstrong, Peter R. Baker II, Nichole A. Reisdorph, Laura D. Brown

12:15 p.m. - 12:30 p.m.

O-064: Glucocorticoids Modify Drug Transporter Activity in Human Fetal Brain Endothelial Cells
Nikola Ivanovski, Phetcharawan Lye, Enrrico Bloise, Stephen G. Matthews

Preeclampsia I

Moderators:
Stella Goulopoulou, PhD
Amy Wooldridge, PhD

E219A

11:00 a.m. - 11:15 a.m.

President's Presenter Award
O-065: Preeclamptic and Normotensive iPSC-Derived Endothelial Cells Have Distinct Responses to Maternal Circulating Factors
Xi D Plummer, Yanming Wu, Purnima Iyer, Pedro Medina, Nazish Sayed, Virginia D Winn

11:15 a.m. - 11:30 a.m.

Kusum Lata Excellence Award
O-066: PFAS Exposure Impairs Vascular Function in Placental Chorionic Plate Arteries and Increases Preeclampsia Risk
Pankaj Yadav, Alissa Hoffman, Ruolin Song, Jay Mishra, Sathish Kumar

11:30 a.m. - 11:45 a.m.

O-067: Mitochondrial Fission is Involved in Rat Uterine Artery Constriction.
Desirae Escalera, Nataliia Hula, Styliani Goulopoulou

11:45 a.m. - 12:00 p.m.

O-068: Improvement in Heart Function in Preeclamptic Rats After Treatment with a G Protein-Coupled Estrogen Receptor Agonist
Allan KN Alencar, Kenneth F Swan, Mistina M Manoharan, Sarah H Lindsey, Gabriella C Pridjian, Michael R Garrett, Carolyn L Bayer

12:00 p.m. - 12:15 p.m.

O-069: Low-Dose Aspirin Improves Uterine Artery Function in a Rat Model of Excessive Hypercholesterolemia in Pregnancy
Amanda A. de Oliveira, Floor Spaans, Murilo E. Graton, Raven Kirschenman, Christy-Lynn M. Cooke, Sandra T. Davidge

12:15 p.m. - 12:30 p.m.

President's Presenter Award
O-070: A Novel Role for Soluble FMS-Like Tyrosine Kinase-1 to Upregulate Trophoblast Leptin Production and Induce Vascular Endothelial Dysfunction in Preeclampsia
Mona Elgazzaz, Safia Ogbi, Gibson Cooper, Kristin Backer, Padmashree Chaudhury Woodham, James Maher, Jessica Faulkner

Gynecology II

Moderators:
Moderator I Details Coming Soon
Lindsey Burnett, MD, PhD

E219BC

11:00 a.m. - 11:15 a.m.

O-071: Pharmacogenomics of the Etonogestrel Contraceptive Implant: A Genome Wide Association Study of Reported Bleeding and Spotting Days
Aaron Lazorwitz, Christina L Aquilante, Jonathan A Shortt, Christopher R Gignoux, Stephanie Teal, Jeanelle Sheeder

11:15 a.m. - 11:30 a.m.

O-072: BMP4 Prevents Thrombin-Induced Endometrial Endothelial Dysfunction and Inflammation: Therapeutic Implications for Abnormal Uterine Bleeding
Cemre Su Kayisli, Asli Ozmen, Busra Cetinkaya-Un, Burak Un, Joseph Huang, Frederick Schatz, Charles J Lockwood

11:30 a.m. - 11:45 a.m.

O-073: Neuron-Enriched Extracellular Vesicle MicroRNA Alterations Associated with Early Life Oral Contraceptive Use
Roxann Roberson-Nay, Vasily Yakovlev, Rebekah L Frye, Timothy P York, Dana M Lapato

11:45 a.m. - 12:00 p.m.

O-074: Menstrual Irregularity is Associated with Central Adiposity and Insulin Resistance Among Samoan Females
Sakurako Oyama, Courtney Choy, Melania Selu, Maria Arorae, Kima Faasalele-Savusa, Muagututia Sefuiva Reupena, Take Naseri, Veronika Shabanova, Clare Flannery, Nicola Hawley

12:00 p.m. - 12:15 p.m.

O-075: Environmental Chemicals in Hair Care Products Used by Black Women Enhance Key Processes in Uterine Fibroid Pathogenesis
Eden D Cohen, Amanda Kallen, Shannon D. Whirledge

12:15 p.m. - 12:30 p.m.

President's Presenter Award
O-076: Single-Cell Transcriptomics Illustrates Distinct Peritoneal Immune Cell Composition in Endometriosis

Mingxin Shi, Vijay Kumar Sirohi, Nash Moawad, Paul Cooke, James MacLean, Kanako Hayashi

Parturition II

Moderators:
Moderator I Details Coming Soon
Angela DeTomaso

E219D

11:00 a.m. - 11:15 a.m.

Chinese Program Travel Award
O-077: The Predictive Value of Biomarkers in Combination with Uterine Electromyograhpy in Symptomatic Women
Pin Li, Miaoting Zhou, Qian Huang, Xueya Qian, Yunshan Chen, Zheng Zheng, Huishu Liu

11:15 a.m. - 11:30 a.m.

O-078: Functional Effects of Oxytocin Receptor Glycosylation
Kaci T Martin, Erin L Reinl, Kevin K Prifti, Melissa G Gibson, Sarah K England, Antonina I Frolova

11:30 a.m. - 11:45 a.m.

O-079: Subchorionic Hematoma Transforms Amnion Mesenchymal Cells into Myofibroblasts and Causes Fibrosis of Fetal Membranes
Eriko Yasuda, Haruta Mogami, Sunao Matsuzaka, Yu Matsuzaka, Asako Inohana, Masahito Takakura†, Yusuke Ueda, Yosuke Kawamura, Yoshitsugu Chigusa, Masaki Mandai

11:45 a.m. - 12:00 p.m.

O-080: Diet-Induced Obesity in Mice Disrupts Mitochondrial Dynamics and Ultrastructure in the Uterus at Term
Kevin K Prifti, Ruth M Gill, Wandy L Beatty, Jordan L Rich, Antonina I Frolova

12:00 p.m. - 12:15 p.m.

O-081: A Broad-Spectrum Chemokine Inhibitor Prevents Preterm Labor in Mice by Suppressing Intra-Amniotic Inflammation
Adam Boros-Rausch, Nicole Ballan, Anna Dorogin, Lubna Nadeem, Oksana Shynlova, Stephen Lye

12:15 p.m. - 12:30 p.m.

O-082: Predictive Factors for Emergency Cervical Cerclage Efficacy: a Retrospective Case Series
Cecile C Hulshoff, Marc E.A. Spaanderman, Ralph R Scholten, Joris Van Drongelen

Reproductive Endocrinology and Infertility I

Moderators:
Nanette Santoro, MD
Moderator II Details Coming Soon

E221

11:00 a.m. - 11:15 a.m.

O-083: The Association Between Total Fetal Fraction of Cell Free DNA and Adverse Pregnancy Outcomes in ART Cycles
Milana Bochkur Dratver, Charikleia Kalliora, Jessica Tozour, Olivia Hatton, Sneha Mani, Nathan Koelper, Suneeta Senapati, Monica Mainigi

11:15 a.m. - 11:30 a.m.

O-084: Hysteroscopic Lysis of Adhesions Before IVF is Associated with Lower Live Birth Rates but Similar Cumulative Live Birth Rates When Compared to Controls
Adi Steinhart, Kaleb Noruzi, Sarah Rubin, Shmuel Sashitsky, Martin Keltz

11:30 a.m. - 11:45 a.m.

O-085: Pharmacologic Inhibition of the Inflammatory Cascade Protects Against Alkylating Ovotoxicity in Mice
Limor Man, Christopher Moutos, Jadyn Matthews, Laury Arazi, Zev Rosenwaks, Daylon James

11:45 a.m. - 12:00 p.m.

President's Presenter Award
O-086: Umbilical Cord Mesenchymal Stem Cell Derived Exosomes Ameliorate Testicular Toxicity Caused by Cyclophosphamide In Vivo
Mervat Mostafa Omran, Farzana Liakath Ali, Omer Raheem, Ayman Al-Hendy

12:00 p.m. - 12:15 p.m.

President's Presenter Award
O-087: Androgen Production by Ovarian Theca Cells is Augmented by FSH-Dependent Stimulation of Prostaglandin E2 Production by Granulosa Cells
Jacey Hu, Chelsea Fox, Lingzhi Zhang, Benjamin Moeller, Antoni J Duleba

12:15 p.m. - 12:30 p.m.

O-088: Role of Insulin Hypersecretion in a Mouse Model of Polycystic Ovary Syndrome
Emma J Houston, Nicole M Templeman

12:30 p.m. - 1:30 p.m.

Diversity, Equity & Inclusion Forum - Playing the Game: Challenges, Changes, and Wins
*Boxed lunches were available for purchase through online registration only.

Moderated by the SRI Diversity, Equity & Inclusion Committee.

The 2025 DEI Forum will consist of a panel of diverse experts including:

Amy Murtha, MD
Dean
Rutgers Robert Wood Johnson Medical School

Shruthi Mahalingaiah, MD, MS
Director of Clinical Research
Director of the Polycystic Ovarian Syndrome Clinic
Massachusetts General Hospital

Owen Vaughan, PhD
Lecturer in Fetal Physiology and Prenatal Therapy
University College London

Richardson Ballroom CD

1:45 p.m. - 3:45 p.m.

Concurrent Mini-Symposia II

Reproductive Sciences at the crossroads of Physiology and Engineering

Moderators:
Hari Eswaran, PhD
Kristin Miller, PhD

E217

1:45 p.m. - 2:15 p.m.

Pelvic Floor Muscles in Pregnancy and Postpartum With Non-Invasive Magnetomyography
Diana Escalona-Vargas, PhD

2:15 p.m. - 2:45 p.m.

Four-dimensional electrical activation pattern during human uterine contraction and peristalsis
Yong Wang, PhD

2:45 p.m. - 3:15 p.m.

Integrating imaging and computational modelling to provide new insight into fetal growth restriction
Jo James, PhD

3:15 p.m. - 3:45 p.m.

Clinical applications of novel placental imaging
Anna David, PhD, FRCOG

Innovations and Future of Reproductive Sciences

Moderators:
Begum Mathyk, MD
Irina Burd, MD, PhD

E219A

1:45 p.m. - 2:15 p.m.

Nanotechnology to advance drug delivery in the female reproductive tract
Hannah Zierden, PhD

2:15 p.m. - 2:45 p.m.

Reproductive Endocrinology to the Moon and Beyond
Begum Aydogan Mathyk, MD

2:45 p.m. - 3:15 p.m.

In vitro manipulation of reproductive tissues to advance women’s health
Shuo Xiao, PhD

3:15 p.m. - 3:45 p.m.

Innovative approaches for the fertility preservation
Hang-soo Park, PhD

Stem Cells, Organoids and Assembloids in Reproductive Medicine

Moderators:
Irene Cervello, PhD
Kenichiro Motomura, MD, PhD

E219BC

1:45 p.m. - 2:15 p.m.

Engineered biomimetics for ovarian folliculogenesis and function in vitro and in vivo
Ariella Shikanov, PhD

2:15 p.m. - 2:45 p.m.

Trophoblast Stem Cell Models for Studying Early Events of Placentation
Kaela Varberg, PhD

2:45 p.m. - 3:15 p.m.

Human Organoids for Endometrial diseases
Hugo Vankelecom, PhD

3:15 p.m. - 3:45 p.m.

Patient-Derived Organoids
Bas Van Rijn, MD, PhD

Epigenetics and Epitranscriptome in reproductive health

Moderators:
Nanbert Zhong, MD
Qiwei Yang, PhD

E219D

1:45 p.m. - 2:15 p.m.

Exploring Epigenetic Mechanisms Influencing Endometriosis Risk
Sally Mortlock, DPhil

2:15 p.m. - 2:45 p.m.

Epigenetic regulation of transposable elements to reverse ovarian cancer immune evasion
Katherine Bakshian Chiappinelli, PhD 

2:45 p.m. - 3:15 p.m.

Molecular basis of MED12 in the pathogenesis of uterine fibroids
Thomas Boyer, PhD

3:15 p.m. - 3:45 p.m.

Introducing new technologies into actual practice
Mark Evans, MD

3:45 p.m. - 4:00 p.m.

Coffee Break

4:00 p.m. - 5:30 p.m.

Concurrent Oral Presentations III

The Future of Reproductive Regenerative Medicine

Moderators:
Jennifer Mitchell, PhD, BSc
Moderator II Details Coming Soon

E217

4:00 p.m. - 4:15 p.m.

O-089: Bioengineered 3D In Vitro Human Myometrium: A New Approach to Quantify Myometrial Contractility
Claudia A Collier, Anirudh K Madyastha, Kaci Martin, Antonina I Frolova, Shreya A Raghavan

4:15 p.m. - 4:30 p.m.

O-090: Cervical Repair in a Rat Model of Cervical Insufficiency Using Platelet-Rich Plasma-Embedded Alginate Hydrogel
lham Ahmadi, Mahya Soleimani Mehranjani, Arya Afrooghe, Kazemi Maryam, Hantoushzadeh Sedigheh, Masoumeh Majidi Zolbin

4:30 p.m. - 4:45 p.m.

O-091: Leveraging Host Omic-Response Signatures to Identify Microbiome Metabolizers of Drugs: A Case Study of Tenofovir Metabolism by the Vaginal Microbiome
Dali Nemecio, Douglas Brubaker

4:45 p.m. - 5:00 p.m.

O-092: Human Umbilical Cord Mesenchymal Stem Cell Derived Exosomes Ameliorate Age-Related Decline in Testosterone by Inhibiting Leydig Cell Apoptosis through Modulating PTEN and PI3K AKT Pathways in a Naturally Aging Mouse Model
Farzana Liakath Ali, Mervat Omran, Omer Raheem, Hang-Soo Park, Mohammad Mousaei, Ayman Al-Hendy

5:00 p.m. - 5:15 p.m.

O-093: A Tunable Vaginal Extracellular Matrix Hydrogel for 3D Vaginal Fibroblast Culture and Biofabrication
Morgan Egnot, Marrisa Therriault, Zachary Miller, Cecilia Schiavoni, Nisha Shetty, Amanda Artsen, Bryan N Brown, Pamela Moalli

5:15 p.m. - 5:30 p.m.

O-094: Phenotyping Adolescent Endometriosis: Characterizing Symptom Heterogeneity Through Note- and Patient-Level Clustering
Rebecca M Cohen, Emily Leventhal, Nivedita Nukavarapu, Kimberly B Glazer, Michal A Elovitz, Victoria Lazarov, Sarriyah Hanif, Ipek Ensari

Developmental Programming II

Moderators:
Sathish Kumar, DVM, PhD
Murilo Graton, PhD

E218

4:00 p.m. - 4:15 p.m.

O-095: Cardiopulmonary Hemodynamics in the Transition to Ex-Utero Life in Preterm Growth Restricted Lambs
Beth J Allison, Mikee Inocencio, Valerie Zahrah, Amy Sutherland, Beth R Piscopo, Matthew Oyang, Stuart B Hooper, Graeme R Polglase, Suzie L Miller

4:15 p.m. - 4:30 p.m.

O-096: Inhibiting miR-142-5p Mitigates Fetal Cardiac Dysfunction in a Mouse Model of Maternal Obesity
Gabrielle K Crombie, Daniel J Stuckey, Makrina D Savvidou, Owen R Vaughan

4:30 p.m. - 4:45 p.m.

President's Presenter Award
O-097: Sex Specific Differences in Developmental Programming of the Guinea Pig Near-Term Fetal Kidney with Growth Restriction, and the Influence of Placenta Gene Therapy
Rebecca Wilson, Baylea Davenport, Helen Jones

4:45 p.m. - 5:00 p.m.

O-098: Deleting the RPS6KB1 Gene Encoding the Kinase p70S6K1 Ameliorates Congenital Heart Defects in Diabetic Pregnancy
Mohammad Sazzadul Islam, Md Masud Rana, Wei-Bin Shen, Montasir Elahi, E Albert Reece, Peixin Yang

5:00 p.m. - 5:15 p.m.

O-099: Altered DNA Methylation Profiles In Neonatal Blood Following Exposure To Maternal Depression In Early Gestation
Bona Kim, Stephen G Matthews

5:15 p.m. - 5:30 p.m.

O-100: Male but Not Female Offspring from a Rat Model of Preeclampsia Have Worse Stroke Outcome That Was Prevented by Low-Dose Aspirin Treatment of Dams during Pregnancy.
Marilyn Jo Cipolla, Sarah Tremble

Reproductive Biology II

Moderators:
Moderator I Details Coming Soon
Patricia Diaz-Gimeno, PhD

E219A

4:00 p.m. - 4:15 p.m.

O-101: Synthetic Hydrogel Co-Culture Platform Reveals Crosstalk Between Endometrial Epithelial-Stromal Cells via Transforming Growth Factor Beta 2
Andrew Z Ding, Heather George, Shu-Wing Ng, Linda G Griffith, Douglas A Lauffenburger

4:15 p.m. - 4:30 p.m.

President's Presenter Award
O-102: Human Blastocyst Invasion in a 3D In Vitro Endometrial Model
María Pardo-Figuerez

4:30 p.m. - 4:45 p.m.

O-103: Serial Intravascular Labeling Highlights Tissue Residency Alterations in Trafficking NK Cells during Pregnancy
Mona A Mohamed, Jessica Vazquez, Fernanda Leyva Jaimes, Aleksandar K Stanic

4:45 p.m. - 5:00 p.m.

O-104: Serum Response Factor and Myocardin Cooperate with Progesterone Receptor to Mediate Oviductal Embryo Transport
Ryan M. Marquardt, Peter F. Lais, Tianyuan Wang, San-Pin Wu, John P. Lydon, Francesco J. DeMayo

5:00 p.m. - 5:15 p.m.

O-105: Novel Endometrium Receptivity Markers Revealed by Integrated Bulk and Single-Cell RNA Sequencing
Manisha D Persaud, Gregory W Burns, Emmanuel N Paul, Qingshi Zhao, Jessica Garcia De Paredes, Ripla Arora, Nataki C Douglas, Anat Chemerinski

5:15 p.m. - 5:30 p.m.

O-106: Dynamic Uterine Fluid Absorption Regulated by Uterine Epithelial ERα and PR during Early Pregnancy
Xiaoqin Ye, Jonathan Hancock, Taylor E Martin, Yuehuan Li, Venkata Atluri, Jackson Sundgren

Placenta II

Moderators:
Kaela Varberg, PhD
Irving Aye, PhD

E219BC

4:00 p.m. - 4:15 p.m.

President's Presenter Award
O-107: Activin and FSTL3 Possess Opposing Actions Required for Hemochorial Placentation
Mikaela E Simon, Khursheed Iqbal, Ayelen Moreno-Irusta, Regan L Scott, Esteban M Dominguez, Marija Kuna, Kaela M Varberg, Geetu Tuteja, Michael J Soares

4:15 p.m. - 4:30 p.m.

O-108: The Role of Estrogen in Regulating Placental Immune Function in Non-Human Primates
Sahar Khoshravesh, Anguo Liu, Jeffery Babischkin, Graham W Aberdeen, Eugene D Albrecht, Jun Lei, Irina Burd

4:30 p.m. - 4:45 p.m.

O-109: Trophoblast Modulates Immune Responses Despite Simultaneous Anti‑PD‑L1 Treatment
Jessica J. R. Jank, Hannah Wein, Damián O. Muzzio, Marek Zygmunt

4:45 p.m. - 5:00 p.m.

O-110: PRMT1 Equipoises Epigenetic Regulation in Trophoblast Development to Prevent Early Pregnancy Losses
Purbasa Dasgupta, Rajnish Kumar, Soma Ray, Namrata Roy, Asef Niloy, Soumen Paul

5:00 p.m. - 5:15 p.m.

O-111: Derivation of Human Trophoblast Stem Cells from Term Cytotrophoblasts
John W. Britt, Mahe Jabeen, Victoria Karakis, Adriana San Miguel, Balaji Rao

5:15 p.m. - 5:30 p.m.

O-112: Recapitulating Placental Development Through Co-Culture of Human Trophoblast and Embryonic Stem Cells
Lishi Ma, Mark Kibschull, Stephen Lye

Reproductive Endocrinology and Infertility II

Moderators:
Sarah Berga, MD
Jaime Roura-Monllor, MD, MS

E219D

4:00 p.m. - 4:15 p.m.

O-113: Ovarian Androgen Secretion is Reduced Following Suppression of Lipid-Induced Inflammation with a Nonsteriodal Anti-Inflammatory Agent in Women with Polycystic Ovary Syndrome (PCOS)
Frank Gonzalez, Ana-Leonor Jay, Jiaping Xue, Lixin Qi

4:15 p.m. - 4:30 p.m.

O-114: Metformin Attenuates Endotoxemia and Reduces Ovarian Theca Androgen Production in Women with Polycystic Ovary Syndrome
Katherine J Kim, Beata Banaszewska, Mateusz Trzcinski, Piotr Piekarski, Leszek Pawelczyk, Antoni J Duleba

4:30 p.m. - 4:45 p.m.

O-115: An Ex Vivo Model of Polycystic Ovary Syndrome (PCOS) to Identify Key Gene Regulatory Pathways Driving PCOS-Induced Ovarian Disorders
Lauren Gibbs, Ying Zhang, Pawat Pattarawat, Hongyi Xu, Kuhelika Mali, Ji-Yong Julie Kim, Teresa Woodruff, Shuo Xiao

4:45 p.m. - 5:30 p.m.

President's Presenter Award
O-116: Modelling Early Embryo-Endometrial Interactions: Insights from a 3D Culture System for Human Implantation on Differential Secretome Dynamics in Euploid and Aneuploid Embryos.
Andrea Palomar, Roberto Yagüe, Alicia Quiñonero, Morales Sara, Mireia Florensa, Amparo Mercader, Pilar Alama, Jose Remohí, Matteo Molè, Imma Sánchez, Francisco Dominguez

5:00 p.m. - 5:15 p.m.

O-117: Decellularization of Human Ovaries and Hydrogels Development: Towards Clinical Translation
Emilio Francés-Herrero, Clara Bueno-Fernandez, María Gómez-Álvarez, Marcos Agustina-Hernández, Paula Alonso-Frías, Amparo Faus, Antonio Pellicer, Irene Cervelló

5:15 p.m. - 5:30 p.m.

O-118: Spatiotemporal mRNA Targeting to the Endometrium for the Treatment of Female Infertility
Saed A. Abbasi

Clinical and Translational Perinatology II

Moderators:
Jean Goodman, MD MBA
Moderator II Details Coming Soon

E221

4:00 p.m. - 4:15 p.m.

O-119: Impact of SARS-CoV-2 in Pregnancy on Early Childhood Growth and Development
Ofer Beharier, Joshua Guedalia, Dvora R. Sehtman-Shachar, Liya Kerem, Adva Cahen-Peretz, Sarah M. Cohen, Yishai Sompolinsky, Galit Shefer, Eli Melul, Debra Goldman-Wohl, Simcha Yagel, Ronit Calderon-Margalit, Michal Lipschuetz

4:15 p.m. - 4:30 p.m.

O-120: Characterizing Environmental Risk for Preterm Birth Using Objective and Subjective Measure of Neighborhood Disorder
Shawn J Latendresse

4:30 p.m. - 4:45 p.m.

O-121: Residing in a Pharmacy Desert and Adverse Pregnancy Outcomes: A Geospatial Study
Blake A Neuburg, William A Grobman, Wu Jiqiang, Sadiya S Khan, Kartik K Venkatesh

4:45 p.m. - 5:00 p.m.

O-122: Neonatal Outcomes in Obese Patients Administered Betamethasone: A United States National Perspective
Zimeng Gao, Shaun Wesley, Alexsaundra Zywicki, Sarah Crimmins

5:00 p.m. - 5:15 p.m.

O-123: Impact of Peri-Conceptional Exposure to Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists on Perinatal and Neonatal Outcomes
Darios Getahun, Wudeneh M Mulugeta, Morgan R Peltier, Vicki Y Chiu, Fagen Xie, Theresa M Im, Nehaa Khadka, Alexa N Reilly, Jiaxiao M Shi, Michael J Fassett

5:15 p.m. - 5:30 p.m.

O-124: Do Peripartum Morbidities Increase the Risk of Developing Postpartum Depression?
Audrey Marinelli, Lisbet Lundsberg, Caitlin Partridge, Jennifer Culhane

5:45 p.m. - 7:00 p.m.

Presidential Address and Awards Ceremony

Richardson Ballroom CD

8:30 p.m. - 11:00 p.m.

The Featles

Richardson Ballroom CD

7:00 a.m. - 1:00 p.m.

Registration

Concourse C

7:30 a.m. - 8:15 a.m.

SRI Member Business Meeting
*All SRI Members are invited to attend, including in-training members. Breakfast will be available starting at 7:00 a.m.

Richardson Ballroom CD

8:20 a.m. - 8:30 a.m.

Welcome & Announcements

Richardson Ballroom CD

8:30 a.m. - 9:20 a.m.

2024 March of Dimes Richard B. Johnston, Jr., MD Prize in Developmental Biology Award

Richardson Ballroom CD

9:30 a.m. - 11:30 a.m.

Poster Session III

Hall C2

11:30 a.m. - 1:00 p.m.

Concurrent Oral Presentations IV

Fetus II

Moderators:
Bill Pearce, PhD
Kathryn Gray, MD, PhD

E217

11:30 a.m. - 11:45 a.m.

President's Presenter Award
O-125: Tadalafil Therapy for Protecting the Fetal Heart Against Injury: Studies in the Chicken Embryo
Dave Duru, Shintaro Maki, Youguo Niu, Tomoaki Ikeda, Dino A Giussani

11:45 a.m. - 12:00 p.m.

O-126: Advanced Magnetic Resonance Spectroscopy: Navigating the Challenges of Investigating Fetal Brain Metabolism
Jordan A Minns, Jack RT Darby, Stacey L Holman, Brahmdeep S Saini, Georgia K Williams, Steven Miller, Mike Seed, Janna L Morrison

12:00 p.m. - 12:15 p.m.

O-127: Restoring the Expression of an Autophagy Gene Ambra1 Ameliorates Endoplasmic Reticulum Stress and Neural Tube Defects in Diabetic Pregnancy
Md Mahadi Hassan, Bingbing Wang, E. Albert Reece, Peixin Yang

12:15 p.m. - 12:30 p.m.

Laxmi Baxi Award
O-128: Antenatal Melatonin Treatment Restores Hippocampal Structure and Function in Newborn and 4-Week-Old Fetal Growth Restricted Lambs
Tegan A White, Charmaine R Rock, Beth R Piscopo, Amy E Sutherland, Yen Pham, Beth J Allison, Emily J Camm, Suzanne L Miller

12:30 p.m. - 12:45 p.m.

O-129: Maternal 3-Hour Placental Lactogen Infusions Increase Fetal Glucose Uptake in Hyperglucagonemic Fetuses by Regulating Placental Utilization
Amelia R Tanner, Marjorie A Nguygen, Russell V Anthony, Paul J Rozance

12:45 p.m. - 1:00 p.m.

O-130: Single-nucleus Transcriptomics Reveals Maternal Inflammation Impairs Synaptic Signaling: A novel mouse model for fetal neurodevelopment
Weina Ju, Cherilyn Uhm, Yong Liu, Elizabeth A. Bonney, Nanbert Zhong

Gynecology III

Moderators:
Marsha Guess, MD
Md Soriful Islam, PhD

E218

11:30 a.m. - 11:45 a.m.

O-131: Lyme Disease Increases Risk for Uterine Conditions and Gynepathologies.
Paige Hansen Colburn

11:45 a.m. - 12:00 p.m.

O-132: The Role of CXCR3 in Vaginal Wound Healing
Nisha Shetty, Kristina Weber, Krystyna Rytel, Katrina Knight, Pamela Moalli, Amanda Artsen

12:00 p.m. - 12:15 p.m.

O-133: Dysregulation of ECM Genes by an Altered Decidualization Response in Endometriosis
Virgil Bideau, Bijaya Nayak, Zhao Zhang, Bruce Nicholson, Nameer Kirma

12:15 p.m. - 12:30 p.m.

President's Presenter Award
O-134: Characterizing Heterogeneity of Estrogen Receptor Isoform Expression in Endometriosis: Rethinking the ERβ Dominance Hypothesis
Alexis E Heath, Douglas Brubaker

12:30 p.m. - 12:45 p.m.

Early Career Investigator Award
O-135: Deficient Ovarian Reserve and Abnormal Steroid Hormone Response in a Spontaneous Ovarian Endometrioma Mouse Model
Yuliya Klymenko, Oyinkasola Adeomojo, Jillian R Wendel, Xiyin Wang, Robert Emerson, Shannon M Hawkins

12:45 p.m. - 1:00 p.m.

O-136: A Novel Therapeutic Approach to Improve Pain and Subfertility in Endometriosis Using Conditioned Medium of Umbilical Cord-Derived Mesenchymal Stem Cells
S. Joseph Huang, Chun-Yen Huang, Ya-Chun Yu, Yun-Hsiang Hung, Chih-Chen Chen, Li-Yen Shiu

Placenta III

Moderators:
Yingshi Ouyang, PhD
Regan Scott, MS

E219A

11:30 a.m. - 11:45 a.m.

O-137: Endothelial PAS Domain-Containing Protein 1 Involvement in Hemochorial Placental Development
Sri Vidya Dangudubiyyam, Marija Kuna, Vinay Shukla, Masanaga Muto, Khursheed Iqbal, Michael J. Soares

11:45 a.m. - 12:00 p.m.

O-138: Role of Aspirin in Modulating Immune Responses and Reducing CMV Transmission in Pregnancy
Vinay Shukla, Saima Khatoon, Sahar Khoshravesh, Anguo Liu, Jun Lei, Irina Burd

12:00 p.m. - 12:15 p.m.

O-139: Mitochondrial Glutamine Metabolism Regulates Trophoblast Differentiation
Cassandra Norbeck, Snehalata Jena, Renee Mahr, Alisa Nelson, Eric Queathem, Patrycja Puchalska, Peter Crawford, Micah Gearhart, Sarah Wernimont

12:15 p.m. - 12:30 p.m.

O-140: Aberrant Placental Architecture is Corrected with Repeated Nanoparticle-Mediated, Trophoblast-Specific hIGF1 Therapy in a Guinea Pig Model of Fetal Growth Restriction
Baylea Davenport, Rebecca Wilson, Helen Jones

12:30 p.m. - 12:45 p.m.

O-141: Trophoblast Stem Cell Macrophage Co-Culture Model of the Maternal Fetal Interface Closely Resembles Primary Tissue Explant Model
Caroline Smith, Rebecca Zack, Emale El Darzi, Taylor Snisky, Christina Megli

12:45 p.m. - 1:00 p.m.

O-142: Mechanosensitive PIEZO1 Channel Regulates Trophoblast Differentiation and Placental Development.
Yang Zhang, Ke Shan, Pengfei Liang, Huanghe Yang

Reproductive Biology III

Moderators:
Moderator I Details Coming Soon
Rahul D'Mello, MD, PhD

E219BC

11:30 a.m. - 11:45 a.m.

President's Presenter Award
O-143: Dynamics of Macrophage Polarization Reveal Unique Phenotypes during Mouse Postpartum Uterine Remodeling
Maria Natalia Chaves Rivera, Sydney Bell, Abigail Solomon, Aya Tal, Reshef Tal

11:45 a.m. - 12:00 p.m.

Carole Mendelson Award
O-144: Progesterone-Mediated Differentiation of Uterine Tissue-Resident NK Cells
Dorothy K. Sojka, Bruna K. Tatematsu

12:00 p.m. - 12:15 p.m.

President's Presenter Award
O-145: Extracellular Vesicles from Human Semen Induce Emigration and Phenotypic Changes of Mucosal Dendritic Cells, and Shape Regulatory T Cell Differentiation
Shahrokh Paktinat, Michael G. Gravett, Cara Tobey, Germán G. Gornalusse, Maryam Kalatehjari, Florian Hladik, Lucia Vojtech

12:15 p.m. - 12:30 p.m.

Early Career Investigator Award
O-146: Identification of ALDH1A1⁺ Cells as Endometrial Progenitors with Long-Term Regenerative Capacity
Diana Monsivais, Suni Tang, Anna Catherine Unser, Ting Geng, Zian Liao, Sydney Parks, Peixin Jiang, Linda Alpuing Radilla, Xiaoming Guan

12:30 p.m. - 12:45 p.m.

O-147: Understanding the Contribution of Mesenchymal-Epithelial Transition to Postpartum Endometrial Repair
Zidao Wang, Amanda Patterson

12:45 p.m. - 1:00 p.m.

O-148: Profiling the Transcellular Biosynthesis of Specialized Pro-resolving Inflammatory Mediators (SPMs) Across Human Endometrial Health and Disease.
Mariana Alonso-Riquelme, Elizabeth E Marr, Peter R Movilla, Mollie A O’Brien, Juan S Gnecco

Preeclampsia II

Moderators:
Moderator I Details Coming Soon
Ar-ris Collier, MD

E219D

11:30 a.m. - 11:45 a.m.

President's Presenter Award
O-149: Toll-Like Receptor 9 Activation Induces Pregnancy and Vascular Bed-Specific Endothelial Dysfunction in Rats
Nataliia Hula, Renee Oliveira da Silva, Desirae Escalera, Isabelle K. Gorham, Nicole R Phillips, Styliani Goulopoulou

11:45 a.m. - 12:00 p.m.

President's Presenter Award
O-150: Systemic Immune Dysregulation Induced by Preeclampsia Persists Years After Delivery
Maximilian Sabayev, Dorien Feyaerts, Ganio A Edward, Stelzer Ina, Masaki Sato, Amelie Cambriel, Thomas Bonham, Zala N Mihalic, Maïgane Diop, Purnima Iyer, Oshra Sedan, Nima Aghaeepour, Martin Angst, Gary M Shaw, David K Stevenson, Mark A Hlatky, Virginia D Winn, Brice Gaudillière

12:00 p.m. - 12:15 p.m.

O-151: First Trimester Molecular Signature of Early Onset Preeclampsia in Plasma Cell-Free RNA Based on Decidualization Resistance
N Castillo-Marco, M Igual, T Cordero, D Ferri, N Bernat-González, Á Gaspar-Gómez, I Muñoz-Blat, R Monfort, PREMOM consortium, C Simón, T Garrido-Gómez

12:15 p.m. - 12:30 p.m.

O-152: Long-Term Cardiovascular Risk in Women with Hypertensive Pregnancy: Insights from Polygenic Risk Scores
Jaakko S Tyrmi, Anna Kivioja, Elli Toivonen, Heini Huhtala, Tiina Jääskeläinen, Johannes Kettunen, Tanja Saarela, Hannele Laivuori

12:30 p.m. - 12:45 p.m.

O-153: Feasibility of Implementing a Standardized Preeclampsia Risk Screening Tool into the Electronic Medical Record
Daniella Rogerson, Carolina Díaz Luévano, Omar Messina, Marni Jacobs, Ayelet Ruppin-Pham, Maryam Tarsa, Cynthia Gyamfi-Bannerman, E. Nicole Teal

12:45 p.m. - 1:00 p.m.

O-154: Hypertensive Disorders in Pregnancy as Risk Factors for Aortic Valve Calcification and Aortic Aneurysm in Middle Age; a Swedish Cohort Study.
Karl Bergman, Elin Täufer-Cederlöf, Anna-Karin Wikström, Lina Bergman, Anna Bengtsson, Linda Lindström, Susanne Hesselman, Christina Christersson

Benign and Malignant Tumors

Moderators:
Shannon Hawkins, MD, PhD
Bhuchitra Singh, MD, MPH, MS, MBA

E221

11:30 a.m. - 11:45 a.m.

O-155: Epithelial Heterogeneity at Single-Cell Resolution of High-Grade Serous Ovarian Cancer Supports Its Dual Origin
Paula Punzon-Jimenez, Victor Lago, Sandra Boldu-Fernandez, Esther Lara-Cuestam, Lucas Minig, Carlos Simon, Aymara Mas

11:45 a.m. - 12:00 p.m.

O-156: Neonatal Maternal Separation Induces Myometrial Changes in a Mouse Model of Early Life Stress Consistent with Leiomyoma Pathology
Paige M Minchella, Amanda Graham, Julie A. Christianson, Warren B. Nothnick

12:00 p.m. - 12:15 p.m.

O-157: Study on the Effectiveness and Safety of 5-Aminolevulinic Acid Photodynamic Therapy for Cervical Squamous Intraepithelial Lesions
Shiyu Zhang

12:15 p.m. - 12:30 p.m.

O-158: Telmisartan and VTP-27999 Reduce Endometrial Cancer Cell Proliferation and Viability
Tess L Symington, Joshua J Fisher, Paul Tooney, Eugenie R Lumbers, Kirsty G Pringle

12:30 p.m. - 12:45 p.m.

O-159: β-Catenin Mutation is Strongly Associated with Aggressive Metastasis in Endometrial Cancer via Epithelial-Mesenchymal Transition.
Shamsun Nahar, Eunhee M. Jeong, Keun Cheon Kim, Tae Hoon Kim, Russell Broaddus, Jae-Wook Jeong

12:45 p.m. - 1:00 p.m.

O-160: ARID1A/B Mutations Drive Dedifferentiation in Endometrial Carcinoma by Reshaping the Chromatin Landscape
Jessica D. St Laurent

1:15 p.m. - 2:15 p.m.

Hot Topics & Awards Ceremony
*Light Lunch Provided

Moderators:
Elizabeth Bonney, MD, MPH
Erica Marsh, MD, MSCI, FACOG

Richardson Ballroom CD

1:15 p.m. - 1:30 p.m.

O-161: First-Trimester Allostatic Load Partially Mediates the Association Between Neighborhood Deprivation and Adverse Pregnancy Outcomes.
Mitali Ray, Reindolf Oppong, Janet Catov, Jewel Scott

1:30 p.m. - 1:45 p.m.

Giorgio Pardi Junior Scientist Award
O-162: Epigenetic Age as a Biomarker for IVF Outcomes: A Potential Novel Approach to Predicting Fertility Success in Young Infertile Women.
Davide Marinello, Marco Reschini, Laura Sichenze, Roberta Bellinghieri, Bianca Magni, Maira Casalechi, Valentina Bollati, Paola Vigano', Edgardo Somigliana, Letizia Li Piani

1:45 p.m. - 2:15 p.m.

Awards Ceremony
Supported in part by the SRI Foundation

• President's Presenter's Awards
• Early Career Investigator Awards
• Carole Mendelson Award
• Laxmi Baxi Awards
• The Kusum Lata Excellence Award
• Giorgio Pardi Junior Scientist Award
• Chinese Program Travel Award
• Poster Awards